Excess weight is undoubtedly one of the major modifiable risk factors for sleep apnea. But we rarely actively help our patients lose weight and many patients who do lose weight often put it back on again (rebound). In this clinical trial we had a clinical nutritionist/exercise physiologist help over 40 of our sleep apnea patients (both those on CPAP and those not on CPAP) lose about 12.9 kg of body mass using a 2 month Very Low Energy Diet program. After that they switched to 1 of 2 maintenance diets and managed to maintain most of their weight loss out to 1 year follow-up regaining only about 3kg. This weight loss maintenance programme piloting two common diets for our obese OSA patients was feasible, tolerable and efficacious for a period of 10 months and may be directly translatable into clinical sleep laboratories in the Australian healthcare system and possibly elsewhere.
2. Share a PubMed or DOI link to article
3. Do you have any ideas to expand upon this research? Are you looking for collaborators?
We are looking at translating this program and/or potentially testing it in combination with other therapies in larger trials