Colour-based nanotechnology for norovirus detection

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1. Summary

Norovirus is the most common cause of viral gastroenteritis in humans. Globally, there are approximately 685 million cases of norovirus infection each year and more than 200,000 deaths. In Australia, over a million cases have been reported with the most recent being in October 2016. This makes norovirus the number one foodborne illness (typically from oysters and berries) and the leading cause of foodborne disease outbreaks globally. Currently patient isolation is the only way to minimise the spread of the virus. Given the highly contagious nature, a rapid way to detect norovirus in food production pipeline and human infections is urgently required to mitigate viral outbreaks.

The detection method should be rapid, easy-to-use, cheap, and suitable for mass screening of large samples to precisely detect very small virus numbers. The current method for norovirus detection relies upon expensive and lengthy analysis of the genetic material of virus. This does not offer an economically viable option for food producers to verify that their food is safe before being released to the community.


To address this problem, we assembled a team of nanotechnologists, chemists and virologists to develop a new technology that is based on simple generation of blue colour, when our nano-chip comes in contact with norovirus. As low as 20 virus particles allow this colour generation within minutes, a number that is relevant for infection to start. The intensity of colour directly corresponds to the number of norovirus, meaning that the brighter the blue colour, the more viruses are present. A colour matching reference strip then allows virus numbers to be determined by the naked eye, without any need for complicated equipment. The concept is similar to a commonly-available pregnancy detection strip. This builds confidence in the success of this next-generation technology to make our societies safer and healthier.

Comments

51
Hitesh bhushan Gupta
almost 3 years ago

Very Innovative

Md. Nuruzzaman
almost 3 years ago

Excellent idea.

Vipul Bansal
almost 3 years ago

Fantastic idea that is easy to translate, low coat and with a very high social impact

Mandeep Singh
almost 3 years ago

Like the idea very much. Believe that the present research community will not much to wait to realise it on practical terms

Smooker Smooker
almost 3 years ago

Great! Should be a mandatory test on every cruise ship!

Oliver Jones
almost 3 years ago

Great idea and very innovative.

Nitin Mantri
almost 3 years ago

Excellent idea! We need more community focused research like this!

Gajendra Jagtap
almost 3 years ago

Practically very useful test for detection of food borne viral pathogen and could be used in trade.

Apoorva Makhale
almost 3 years ago

Very innovative and extremely useful idea. Hope it is implemented in the food industry sector quickly. A need of the hour research!

Hem Raj
almost 3 years ago

excellent idea

Kalpesh Chaphekar
almost 3 years ago

Cooll idea

Jyoti Karmakar
almost 3 years ago

Great idea. For the good of all.

Devika Jayawickrama
almost 3 years ago

Great!!!

Talya Burnaby
almost 3 years ago

Great idea !!

Mayank Kaashyap
almost 3 years ago

Easy and effective!

saumya premaratne
almost 3 years ago

Great

K.V. Satheeshkumar
almost 3 years ago

Fantastic!!!

K.V. Satheeshkumar
almost 3 years ago

Fantastic

Ravi Singh
almost 3 years ago

Great

Ripanjeet Kaur
almost 3 years ago

Cool Concept... like to see how research goes in this field

Mani S
almost 3 years ago

Great.. like the idea

Harbans Singla
almost 3 years ago

V.V.Great

AJWINDER Singh
almost 3 years ago

Great

swatee garg
almost 3 years ago

great idea!!!

Sugantha Narayanan
almost 3 years ago

Great

NIRAJ AGARWAL
almost 3 years ago

We are proud of you, Dr Vipul Bansal.

Amit Agrawal
almost 3 years ago

Proud of you your team bhaiya ...keep shining

Niraj Vats
almost 3 years ago

Keep Shining
God Bless you with Success

Md Sakinul Islam
almost 3 years ago

All the best

Padam Kansal
almost 3 years ago

God bless you... A very innovative idea... Will help the community a lot...

Puninder Kaur
almost 3 years ago

ALL THE BEST !

Arshveer sidhu
almost 3 years ago

innovative

Minnie Kalra
almost 3 years ago

Great... very innovative... good luck.

Jesse D
almost 3 years ago

go team

Tarun Sharma
almost 3 years ago

Innovative work

Tarun Sharma
almost 3 years ago

Innovative work

Neha Bhasin
almost 3 years ago

Great Idea! Good luck :)

A.S. Gharge
almost 3 years ago

VERY NICE AND ALL THE BEST TO YOU

A.S. Gharge
almost 3 years ago

VERY VERY NICE. ALL THE BEST TO YOU DEAR RAJESH

leela r
almost 3 years ago

Great

Leela Ramu
almost 3 years ago

Great effort

BALAJI DHANAVEL
almost 3 years ago

Hats off

Fateh Singh
almost 3 years ago

God bless

Nitesh Agarwal
almost 3 years ago

Good job

Fateh Singh
almost 3 years ago

May vaheguru be with u always

Prakhar Singhal
almost 3 years ago

Great Idea! Good luck vipul bhaiya :)

Prashant Rajani
almost 3 years ago

Best wishes Vipul.....

asghar nawaz
almost 3 years ago

hello

Amar Ghaisas
almost 3 years ago

Wish you all a resounding success in your endeavour! Go team NanoBioSensing!

ajay gupta
almost 3 years ago

research&datacollection is very nice method

ravinder singh
almost 3 years ago

Good luck